Archive for the ‘Uncategorized’ Category

Did Kawaski Syndrome cause Jett Travolta’s Seizure?

Tuesday, February 3rd, 2009

As you may have read in the popular media, John Travolta’s son, Jett, died tragically earlier this month. The cause of death was reported as complications resulting from seizures apparently brought on by his childhood affliction from Kawasaki syndrome, an illness that leads to inflamed blood vessels. This month, searches on terms related to Kawasaki syndrome have increased quite a bit in DeepDyve. And similarly, according to Google Trends, the popularity of that term spiked by near 10X and even surpassed “Obama” and “Paris Hilton” on the days following the story.

There has been some intrigue concerning the details of his death. According to an article in WebMD, there is no association between Kawasaki disease and seizures. This belief has made its way into news articles and the blog world such that there are questions as to whether Travolta’s son actually was autistic, exhibiting a mental condition which is not recognized by his church of Scientology and which commonly leads to seizures.

We decided to do a quick look into this question.  Using DeepDyve, we searched on the phrase “kawasaki syndrome seizures”, we immediately found a “Seizure characteristics in Kawasaki disease” (Shimakawa S, Yamada K, Hara K, Tanabe T, Tamai H; No To Hattatsu 2008 Jul; 40(4):289-94).  The report starts with “It is well known that convulsions may occur in clinical course of Kawasaki disease. However, the features of such seizures remain unclear,” then goes on to present a possible cause, namely “proinflammatory cytokines”.

In The Journal of Child Neurology, we found “Other neurologic associations and complications of Kawasaki disease have been described and include extreme irritability, aseptic meningitis, seizures and meningoencephalitis, facial nerve palsy, subdural collection, ataxia, stroke, and sensorineural hearing loss.”1

We are not maintaining that Jett Travolta’s death was caused by Kawasaki; nor are we refuting the allegations made in these articles.  Our point is merely that there is more science data to this story which challenges the research claims being made by most of the media reports. Given the terrible tragedy and deeply personal innuendo written in so many of the articles, shouldn’t we demand a higher standard of investigation?

1 Entesar Husain and Enamul Hoque; J Child Neurol; “Meningoencephalitis as a Presentation of Kawasaki Disease”; 2006; 21; 1080; DOI: 10.1177/7010.2006.00232

New Scientific Research Available at DeepDyve

Monday, January 19th, 2009

One of the challenges of doing any sort of search on the Web is filtering out the noise.  In the case of doing research, the challenge is even larger as the information you are seeking is often very specific and authoritative.  A large focus for DeepDyve is in bringing these authoritative sources to you and we are pleased to announce the following content sources will be added to our index this month:

Welcome to DeepDyve

Thursday, January 15th, 2009

Greetings!  This is the inaugural post in our new blog that will be a forum for discussions about what’s on our mind – and yours – in the search and information industry.  The vision behind our company is that Search is in its infancy and today’s ‘traditional’ search engines meet only our most basic, albeit common, needs – the fat part of the long tail. However, doing research, looking for that needle in the long-tail haystack, requires a different approach.

In essence, good search of any kind comes down to the strength of the relevance algorithm, the quality and quantity of content to search against, and the ease of use of the product.  Whereas most search today is often narrow, ‘single-concept’ type queries (‘Obama’, ‘restaurant review’, etc.), research queries are inherently ‘multi-concept’ as the user wants to find broad and deep information about a complex subject (for example, starting with “pancreatic cancer treatment options, side effects, current research, clinical trials”; all the way to “effectiveness of selenium for pancreatic cancer”).

This has several implications:

  1. Relevance: there’s so much information on the Web that searching against all this data inevitably produces tremendous noise.  This problem is further exacerbated by search algorithms which use techniques such as PageRank which prioritize results based on popularity.  When you combine these factors, you end up with millions of hits where the top results are irrelevant and you have to sift for hours to find the hidden gems.
  2. Content: as mentioned above, the web is littered with content.  Unfortunately, for research purposes, the vast majority of content are news articles, amateurish and/or commercial.  Researchers want access to the best available information from authoritative sources ideally spanning general, introductory information all the way down to highly-specialized, peer-reviewed literature.
  3. Short/long queries: single-concept queries can easily be described in 3 words or less unlike multi-concept queries where researchers would like the flexibility of describing exactly what they are looking for in a natural language, or alternatively letting “the content be the query” by using a relevant article as an example for finding more articles related to that subject.  In addition, they would like to be able to search across multiple subject areas and not have to recreate their efforts from vertical to vertical.

Our mission at DeepDyve is to build a research engine that is focused on solving these challenges.  Our vision is that the paradigm of ‘research’ is evolving as more individuals take advantage of the incredible wealth of information potentially available to them not just from content sources but also from each other.  The challenge will be how to effectively make this information, and each other, easily accessible. We look forward to sharing our ideas with you on our vision and hearing your thoughts and suggestions as we embark on this journey.